Grh1 sec23
WebMar 20, 2007 · Indeed, coat-dependent tethering may be such an integral part of vesicle consumption that it operates redundantly in COPII vesicle transport. The putative yeast … WebGRH1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) Amino acids. 372. ... Interacts with COPII …
Grh1 sec23
Did you know?
WebJul 1, 2008 · Sec13 and Sec31 exist as a heterotetrameric complex. The Sec23–Sec24 complex is recruited by Sar1 and binds directly to the ER membrane as an ‘inner coat’. … WebThe coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC23 interacts with …
WebNov 11, 2024 · Our model of the Sec23–Grh1 complex contains an interface between the Sec23 gelsolin domain and the PPP motif of Grh1 , and an interface between the Grh1 … WebSec23 homolog A (S. cerevisiae) antibody; SEC23-related protein A antibody; sec23a antibody; see all. Images. Western blot - Anti-SEC23A antibody (ab99552) Anti-SEC23A antibody (ab99552) at 2 µg/ml (incubation time 1 hour) + NIH 3T3 cell lysate in RIPA buffer at 35 µg Developed using the ECL technique.
WebApproximately one-third of the mammalian proteome is transported from the endoplasmic reticulum-to-Golgi via COPII-coated vesicles. SEC23, a core component of coat protein-complex II (COPII), is encoded by two … WebAppears to play a role in the tethering of COPII (CPX-2523), though an interaction with Sec23/24, and thus formation of the cis-Golgi and endoplasmic reticulum to Golgi vesicle …
WebOct 24, 2024 · Furthermore, Grh1 is also able to form amyloid-like fibrils either upon heating or when submitted to changes in the dielectric constant of its surroundings, a condition that is experienced by the protein when in close contact with membranes of cell compartments, such as the Golgi apparatus. Intrinsic disorder and fibril formation can thus be ...
WebNov 16, 2024 · A RESOLUTION proposing an amendment to the Constitution so as to authorize the General Assembly to provide for the proceeds of one or more lottery … marion calvettiWebIn yeast, Grh1p targets the coiled-coil tether Bug1 to the early Golgi and interacts with the COPII Sec23/24 subcomplex (Behnia et al., 2007). In non-biofilm A. nidulans cells, GrhA … dana transport safety complianceWebSep 17, 2013 · The COPII proteins assemble in a particular order to form the vesicle—Sar1 inserts into the membrane of the ER; Sec23 and Sec24 form an inner coat and capture the proteins that the vesicle will transport; and Sec13 and Sec31 form an outer coat. Although the structures of the coat proteins are known, how they bind to each other—and to the … danatra video