WebNiraparib is a useful option for first-line maintenance therapy for advanced ovarian cancer in adults who responded to platinum-based chemotherapy, regardless of homologous-recombination deficiency status and is a promising option for HRp patients, for whom maintenance treatment options are limited. Plain language summary WebDec 1, 2024 · Assuming that a 50% improvement in PFS with docetaxel maintenance therapy would indicate superiority over the BSC group (4.5 vs. 3.0 months), at the level of two-sided α=0.05, β=0.2, with a 2:1 randomization, an enrollment period of 18 months, and a follow-up period of 24 months, the estimated sample size was 270 patients (180 in the ...
Safety and Efficacy Study of Abraxane as Maintenance Treatment …
WebPaclitaxel-carboplatin and bevacizumab therapy is an acceptable and tolerable treatment for advanced or recurrent cervical cancer. Paclitaxel-carboplatin and bevacizumab … WebIn this trial, induction therapy with atezolizumab plus carboplatin and etoposide followed by maintenance therapy with atezolizumab alone significantly prolonged overall survival (OS) and progression-free survival (PFS) compared with carboplatin and etoposide alone. costco auto insurance policy
Veliparib With Carboplatin and Paclitaxel and as …
WebJan 6, 2014 · Safety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. WebJun 25, 2024 · In the phase 1/3 IMpower133 study, atezolizumab plus carboplatin and etoposide (CP/ET) followed by maintenance atezolizumab for first-line treatment of extensive-stage SCLC (ES-SCLC) led to improvement in both overall survival (OS) and progression-free survival (PFS) versus placebo plus CP/ET followed by maintenance … WebSep 28, 2024 · Chemotherapy consisted of carboplatin (given at an area under the curve [AUC] of 6 mg per milliliter per minute, every 3 weeks) and paclitaxel (175 mg per square meter of body-surface area,... lysoform salviettine igienizzanti